A pregnant woman

Can Mayonnaise Cure My Infertility?

This was the title of a newspaper article that appeared in The Guardian a few years ago. The next statement was, “A controversial treatment that has divided medical professionals is offering hope to women who have suffered multiple miscarriages.”

The treatment they are referring to is known as Intralipid Therapy. This is an IV treatment aimed at decreasing natural killer cells in the uterus and has shown to be effective in women suffering from infertility, recurrent miscarriages, and failed IVF attempts.

Intralipid is a 20% fat emulsion that is administered intravenously. The main components are soybean oil, egg yolk, phospholipids and glycerin. It may contain trace amounts of peanut oil, so if you allergic to any of these ingredients, then you should not use Intralipid.

Research has shown that Intralipid enhances successful implantation and maintenance of pregnancies in patients with auto-immune disease, recurrent miscarriages and/ or unsuccessful IVF attempts. Normally, the lining of the uterus contains immune cells that are specially adapted to tolerate an embryo. However, when these ‘friendly’ cells are not present or effective, the mother’s immune system may attack or reject the embryo with so-called ‘natural killer’ (NK) cells. This would make it difficult or impossible for the embryo to implant in the lining of the uterus. Intralipid therapy has been shown to lower the activity of the natural killer cells of our immune system. Studies have shown that Intralipid can help to regulate the NK cells, allowing the embryo to implant on the uterine wall and grow normally.

Intralipid has been used safely for over 30 years. The risks associated with an Intralipid infusion are low. Some patients may experience chills, malaise, headaches, nausea, vomiting, chest pain, shortness of breath, or an allergic type reaction. Intralipid therapy will not be prescribed for you if you have a history of liver failure, kidney disease, hyperlipidemia, or a sensitivity (allergy) to soy, eggs, or peanuts.

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